Each year, across the tropical and subtropical world, thousands of lives are lost or irrevocably damaged by snakebite envenoming. The latest scientific developments—especially a promising “broad‐spectrum” antivenom—have generated hope. But what exactly does this breakthrough mean for rural masses, for farmers, for productivity and development in Asia and Africa? And when, if ever, might it become a transformative relief? Below is a synthesis of the current knowledge, the realistic challenges and the implications for rural livelihoods and global health.